Cellular vimentin regulates the infectivity of Newcastle disease virus through targeting of the HN protein

Abstract The haemagglutinin-neuraminidase (HN) protein plays a crucial role in the infectivity and virulence of Newcastle disease virus (NDV). In a previous study, the mutant HN protein was identified as a crucial virulence factor for the velogenic variant NDV strain JS/7/05/Ch, which evolved from t...

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Bibliographic Details
Published in:Veterinary Research
Main Authors: Xiaolong Lu, Kaituo Liu, Yu Chen, Ruyi Gao, Zenglei Hu, Jiao Hu, Min Gu, Shunlin Hu, Chan Ding, Xinan Jiao, Xiaoquan Wang, Xiufan Liu, Xiaowen Liu
Format: Article
Language:English
Published: BMC 2023-10-01
Subjects:
Newcastle disease virus
HN
vimentin
viral infection
macrophage
Online Access:https://doi.org/10.1186/s13567-023-01230-5

Internet

https://doi.org/10.1186/s13567-023-01230-5

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