The urokinase receptor takes control of cell migration by recruiting integrins and FPR1 on the cell surface.

The receptor (uPAR) of the urokinase-type plasminogen activator (uPA) is crucial in cell migration since it concentrates uPA proteolytic activity at the cell surface, binds vitronectin and associates to integrins. uPAR cross-talk with receptors for the formylated peptide fMLF (fMLF-Rs) has been repo...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Anna Gorrasi, Anna Li Santi, Giuseppina Amodio, Daniela Alfano, Paolo Remondelli, Nunzia Montuori, Pia Ragno
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Online Access:	http://europepmc.org/articles/PMC3897705?pdf=render