DGAT2 partially compensates for lipid-induced ER stress in human DGAT1-deficient intestinal stem cells[S]

Dietary lipids are taken up as FAs by the intestinal epithelium and converted by diacylglycerol acyltransferase (DGAT) enzymes into triglycerides, which are packaged in chylomicrons or stored in cytoplasmic lipid droplets (LDs). DGAT1-deficient patients suffer from vomiting, diarrhea, and protein lo...

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Bibliographic Details

Published in:	Journal of Lipid Research
Main Authors:	Jorik M. van Rijn, Marliek van Hoesel, Cecilia de Heus, AnkeH.M. van Vugt, Judith Klumperman, EdwardE.S. Nieuwenhuis, RoderickH.J. Houwen, Sabine Middendorp
Format:	Article
Language:	English
Published:	Elsevier 2019-10-01
Subjects:	intestine triglycerides diet and dietary lipids diseases fatty acid lipid droplets
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520323105