Synthetic Strategies of Pyrimidine-Based Scaffolds as Aurora Kinase and Polo-like Kinase Inhibitors

The past few decades have witnessed significant progress in anticancer drug discovery. Small molecules containing heterocyclic moieties have attracted considerable interest for designing new antitumor agents. Of these, the pyrimidine ring system is found in multitude of drug structures, and being th...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Mrunal Jadhav, Kaksha Sankhe, Richie R. Bhandare, Zehra Edis, Samir Haj Bloukh, Tabassum Asif Khan
Format:	Article
Language:	English
Published:	MDPI AG 2021-08-01
Subjects:	synthesis aminopyrimidines aurora kinase polo-like kinase anticancer
Online Access:	https://www.mdpi.com/1420-3049/26/17/5170