STIL overexpression shortens lifespan and reduces tumor formation in mice.

Centrosomes are the major microtubule organizing centers of animal cells. Supernumerary centrosomes are a common feature of human tumors and associated with karyotype abnormalities and aggressive disease, but whether they are cause or consequence of cancer remains controversial. Here, we analyzed th...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:PLoS Genetics
المؤلفون الرئيسيون: Amira-Talaat Moussa, Marco R Cosenza, Timothy Wohlfromm, Katharina Brobeil, Anthony Hill, Annarita Patrizi, Karin Müller-Decker, Tim Holland-Letz, Anna Jauch, Bianca Kraft, Alwin Krämer
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Public Library of Science (PLoS) 2024-10-01
الوصول للمادة أونلاين:https://doi.org/10.1371/journal.pgen.1011460