Characterization of the Cynomolgus Macaque Model of Marburg Virus Disease and Assessment of Timing for Therapeutic Treatment Testing

Marburg virus (MARV) causes severe disease and high mortality in humans. The objective of this study was to characterize disease manifestations and pathogenesis in cynomolgus macaques exposed to MARV. The results of this natural history study may be used to identify features of MARV disease useful i...

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Bibliographic Details

Published in:	Viruses
Main Authors:	Elizabeth E. Zumbrun, Carly B. Garvey, Jay B. Wells, Ginger C. Lynn, Sean Van Tongeren, Jesse T. Steffens, Kelly S. Wetzel, Laura M. Gomba, Kristan A. O’Brien, Franco D. Rossi, Xiankun Zeng, Eric D. Lee, Jo Lynne W. Raymond, Diana A. Hoffman, Alexandra N. Jay, Elizabeth S. Brown, Paul A. Kallgren, Sarah L. Norris, Jean Cantey-Kiser, Humza Kudiya, Chris Arthur, Christiana Blair, Darius Babusis, Victor C. Chu, Bali Singh, Roy Bannister, Danielle P. Porter, Tomas Cihlar, John M. Dye
Format:	Article
Language:	English
Published:	MDPI AG 2023-11-01
Subjects:	Marburg virus filovirus nonhuman primate cynomolgus macaque intramuscular animal model
Online Access:	https://www.mdpi.com/1999-4915/15/12/2335