Prioritization and functional assessment of noncoding variants associated with complex diseases

Abstract Unraveling functional noncoding variants associated with complex diseases is still a great challenge. We present a novel algorithm, Prioritization And Functional Assessment (PAFA), that prioritizes and assesses the functionality of genetic variants by introducing population differentiation...

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Bibliographic Details

Published in:	Genome Medicine
Main Authors:	Lin Zhou, Fangqing Zhao
Format:	Article
Language:	English
Published:	BMC 2018-07-01
Subjects:	Complex disease Functional annotation Genetic variant Variant prioritization Noncoding variant
Online Access:	http://link.springer.com/article/10.1186/s13073-018-0565-y