Protein fibril length in cerebrospinal fluid is increased in Alzheimer’s disease
Liquid-based AFM on protein aggregates at single-fibril resolution from the cerebrospinal fluid of patients at various stages of AD reveals that mature fibrils from patients at advanced stage AD have longer length, distinct morphology and spatial organization.
| Published in: | Communications Biology |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-03-01
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| Online Access: | https://doi.org/10.1038/s42003-023-04606-7 |