The Location of the Antimicrobial Peptide Maculatin 1.1 in Model Bacterial Membranes

Maculatin 1.1 (Mac1) is an antimicrobial peptide (AMP) from the skin secretions of Australian tree frogs. In this work, the interaction of Mac1 with anionic phospholipid bilayers was investigated by NMR, circular dichroism (CD) spectroscopy, neutron reflectometry (NR) and molecular dynamics (MD). In...

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Bibliographic Details
Published in:Frontiers in Chemistry
Main Authors: Anton P. Le Brun, Shiying Zhu, Marc-Antoine Sani, Frances Separovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Subjects:
antimicrobial peptide
bicelles
neutron reflectometry
paramagnetic relaxation enhancement
solid-state NMR
solution NMR
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00572/full

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https://www.frontiersin.org/article/10.3389/fchem.2020.00572/full

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