Total neoadjuvant treatment and PD-1/PD-L1 checkpoint inhibitor in locally advanced rectal cancer

For local advanced rectal cancer (LARC), total neoadjuvant treatment (TNT) has shown more complete response (CR), reduced risk of distant metastasis (DM) and increase of the sphincter preservation rate. Now it is the one and only recommendation for high-risk group of LARC according to National Compr...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Weiwei Xiao, Huilong Luo, Ye Yao, Yaqin Wang, Shuang Liu, Rui Sun, Gong Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	locally advanced rectal cancer total neoadjuvant treatment long-course radiotherapy PD-1/PD-L1 short-course radiotherapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1149122/full