Elevated circulating tumor cells reflect high proliferation and genomic complexity in multiple myeloma

Abstract Circulating tumor cells (CTCs) have emerged as a key prognostic factor in newly diagnosed multiple myeloma (NDMM). However, it remains unclear if high CTC counts represent a mere surrogate of tumor burden or might reflect a distinct genomic or transcriptomic entity. In this study, we charac...

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Bibliographic Details

Published in:	HemaSphere
Main Authors:	Juan‐Jose Garces, Benjamin Diamond, Tereza Sevcikova, Serafim Nenarokov, Daniel Bilek, Eva Radova, Ondrej Venglar, Veronika Kapustova, Ross Firestone, Kylee Maclachlan, Anish Simhal, Lucie Broskevicova, Jan Vrana, Ludmila Muronova, Tereza Popkova, Jana Mihalyova, Hana Plonkova, Michael Durante, Bachisio Ziccheddu, Michal Simicek, Hearn Jay Cho, George Mulligan, Jonathan Keats, David Zihala, Ola Landgren, Roman Hajek, Saad Usmani, Francesco Maura, Tomas Jelinek
Format:	Article
Language:	English
Published:	Wiley 2025-09-01
Online Access:	https://doi.org/10.1002/hem3.70218