Senataxin and R-loops homeostasis: multifaced implications in carcinogenesis

Abstract R-loops are inherent byproducts of transcription consisting of an RNA:DNA hybrid and a displaced single-stranded DNA. These structures are of key importance in controlling numerous physiological processes and their homeostasis is tightly controlled by the activities of several enzymes deput...

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Bibliographic Details

Published in:	Cell Death Discovery
Main Authors:	Veronica Gatti, Sara De Domenico, Gerry Melino, Angelo Peschiaroli
Format:	Article
Language:	English
Published:	Nature Publishing Group 2023-05-01
Online Access:	https://doi.org/10.1038/s41420-023-01441-x