Production of monoclonal antibody of heat-labile toxin A subunit to identify enterotoxigenic Escherichia coli by epitope mapping using synthetic peptides

BackgroundEnterotoxigenic Escherichia coli (ETEC) is a major cause of diarrhea through two enterotoxins, a heat-labile toxin and a heat-stable toxin. These toxins alter the cellular signaling pathways, ultimately triggering an increase in chloride secretion and watery diarrhea.ObjectiveFor the devel...

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Bibliographic Details
Published in:Frontiers in Immunology
Main Authors: Jun-Young Park, Seung-Hak Cho
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1152910/full