Immunomodulatory activity of omadacycline in vitro and in a murine model of acute lung injury

ABSTRACT Cystic fibrosis (CF) is characterized by chronic airway obstruction, infection, and inflammation leading to progressive loss of lung function and eventual respiratory failure. Omadacycline, a tetracycline antibiotic, demonstrates in vitro activity against key CF pathogens, substantial lung...

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Bibliographic Details
Published in:mSphere
Main Authors: Madeline Sanders, Paul Beringer
Format: Article
Language:English
Published: American Society for Microbiology 2024-11-01
Subjects:
acute lung injury
immunomodulatory
omadacycline
pharmacokinetics
pharmacodynamics
Online Access:https://journals.asm.org/doi/10.1128/msphere.00671-24

Internet

https://journals.asm.org/doi/10.1128/msphere.00671-24

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