Thy-1 plays a pathogenic role and is a potential biomarker for skin fibrosis in scleroderma

Thy-1 (CD90) is a well-known marker of fibroblasts implicated in organ fibrosis, but its contribution to skin fibrosis remains unknown. We examined Thy-1 expression in scleroderma skin and its potential role as a biomarker and pathogenic factor in animal models of skin fibrosis. Skin from patients w...

Full description

Bibliographic Details

Published in:	JCI Insight
Main Authors:	Roberta G. Marangoni, Poulami Datta, Ananta Paine, Stacey Duemmel, Marc Nuzzo, Laura Sherwood, John Varga, Christopher Ritchlin, Benjamin D. Korman
Format:	Article
Language:	English
Published:	American Society for Clinical investigation 2022-10-01
Subjects:	Dermatology Immunology
Online Access:	https://doi.org/10.1172/jci.insight.149426