Controlled Release of Bone Morphogenetic Protein-2 Augments the Coupling of Angiogenesis and Osteogenesis for Accelerating Mandibular Defect Repair

Reconstruction of a mandibular defect is challenging, with high expectations for both functional and esthetic results. Bone morphogenetic protein-2 (BMP-2) is an essential growth factor in osteogenesis, but the efficacy of the BMP-2-based strategy on the bone regeneration of mandibular defects has n...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Hao Yao, Jiaxin Guo, Wangyong Zhu, Yuxiong Su, Wenxue Tong, Lizhen Zheng, Liang Chang, Xinluan Wang, Yuxiao Lai, Ling Qin, Jiankun Xu
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Subjects:	bone morphogenetic protein-2 hydrogel mandibular defect osteogenesis angiogenesis
Online Access:	https://www.mdpi.com/1999-4923/14/11/2397