Novel bi-allelic DNAH3 variants cause oligoasthenoteratozoospermia

BackgroundOligoasthenoteratozoospermia (OAT) is a widespread cause of male infertility. One of the usual clinical manifestations of OAT is multiple morphological abnormalities of the sperm flagella (MMAF), which are frequently associated with mutations and defects in the dynein family. However, the...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Shu Li, Zexin Zhang, Linna Xie, Yanqiu Zhao, Hongtai Chen, Shijia Zhang, Yixiang Cai, Bingjie Ren, Wensheng Liu, Songxi Tang, Yanwei Sha
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-10-01
Subjects:	oligoasthenoteratozoospermia dynein intracytoplasmic sperm injection male infertility DNAH3
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1462509/full