Determinants of species-specific utilization of ACE2 by human and animal coronaviruses

Abstract Utilization of human ACE2 allowed several bat coronaviruses (CoVs), including the causative agent of COVID-19, to infect humans directly or via intermediate hosts. However, the determinants of species-specific differences in ACE2 usage and the frequency of the ability of animal CoVs to use...

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Bibliographic Details

Published in:	Communications Biology
Main Authors:	Qingxing Wang, Sabrina Noettger, Qinya Xie, Chiara Pastorio, Alina Seidel, Janis A. Müller, Christoph Jung, Timo Jacob, Konstantin M. J. Sparrer, Fabian Zech, Frank Kirchhoff
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-10-01
Online Access:	https://doi.org/10.1038/s42003-023-05436-3