Myelin Basic Protein and a Multiple Sclerosis-related MBP-peptide Bind to Oligonucleotides
Aptamer ligands for myelin basic protein (MBP) were obtained using the systematic evolution of ligand by exponential enrichment (SELEX) method. Two clones were isolated from a pool of oligonucleotides and tested for MBP targeting. Using purified MBP, we demonstrated the binding activity of the aptam...
| Published in: | Molecular Therapy: Nucleic Acids |
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| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2014-01-01
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| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2162253116303316 |