MNRR1 is a driver of ovarian cancer progression

Cancer progression requires the acquisition of mechanisms that support proliferative potential and metastatic capacity. MNRR1 (also CHCHD2, PARK22, AAG10) is a bi-organellar protein that in the mitochondria can bind to Bcl-xL to enhance its anti-apoptotic function, or to respiratory chain complex IV...

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Bibliographic Details
Published in:Translational Oncology
Main Authors: Hussein Chehade, Neeraja Purandare, Alexandra Fox, Nicholas Adzibolosu, Shawn Jayee, Aryan Singh, Roslyn Tedja, Radhika Gogoi, Siddhesh Aras, Lawrence I. Grossman, Gil Mor, Ayesha B. Alvero
Format: Article
Language:English
Published: Elsevier 2023-03-01
Subjects:
Ovarian cancer
MNRR1
Spheroid formation
Focal adhesion
ECM
Cytoskeleton
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323000086

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http://www.sciencedirect.com/science/article/pii/S1936523323000086

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