Co-existence of EGFR T790M-acquired lung adenocarcinoma and transformation into small-cell carcinoma in different organs after osimertinib treatment. A case report

We report a rare case of a 59-year-old man with EGFR-mutated lung adenocarcinoma who developed osimertinib resistance, with coexisting T790M-positive adenocarcinoma and T790M-negative small-cell carcinoma in different organs. After treatment with gefitinib, chemotherapy, osimertinib, and subsequent...

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書誌詳細

出版年:	Current Problems in Cancer: Case Reports
主要な著者:	Masahide Takeda, Mariko Asano, Sho Sakamoto, Yuka Izumiya, Yuji Okuda, Kazuhiro Sato, Katsutoshi Nakayama
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2025-09-01
主題:	Lung adenocarcinoma transformation into small-cell carcinoma osimertinib
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2666621925000286