A high eosinophil proportion increases the risk of skin-related adverse events induced by apalutamide in patients with prostate cancer

BackgroundSkin-related adverse events (AEs) induced by apalutamide occur frequently in Japanese patients with prostate cancer. However, biomarkers for predicting these skin-related AEs have not yet been identified. Therefore, this study investigated whether the proportion of eosinophils could serve...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Yoshihiko Tasaki, Taku Naiki, Yoshihisa Mimura, Yosuke Sugiyama, Misato Tomita, Toshiharu Morikawa, Takashi Nagai, Rei Unno, Toshiki Etani, Shuzo Hamamoto, Yukihiro Umemoto, Takahiro Yasui, Yoko Furukawa-Hibi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	apalutamide eosinophil prostate cancer pruritus rash
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1681734/full