Comparison of NK alloreactivity prediction models based on KIR-MHC interactions in haematopoietic stem cell transplantation

The biological processes underlying NK cell alloreactivity in haematopoietic stem cell transplantation (HSCT) remain unclear. Many different models to predict NK alloreactivity through KIR and MHC genotyping exist, raising ambiguities in its utility and application for clinicians. We assessed 27 pre...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Adèle Dhuyser, Thomas Remen, Michaël Pérès, Vitalina Chamberlain-Evans, Neda Nemat-Gorgani, Arnaud Campidelli, Sandra Clément, Marie Thérèse Rubio, John Trowsdale, Alice Aarnink, James Traherne
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	KIR MHC HLA alloreactivity prediction natural killer (NK)
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1028162/full