Effects of SGLT2 inhibitors on angiography-derived coronary microcirculatory resistance and clinical outcomes in patients with coronary heart disease and type 2 diabetes: A cohort study

Abstract Background Coronary microvascular dysfunction (CMD) is prevalent in patients with coronary heart disease (CHD) and Type 2 Diabetes (T2DM). Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have cardioprotective effects, however, their impact on microcirculatory function is controversial. I...

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Bibliographic Details

Published in:	Diabetology & Metabolic Syndrome
Main Authors:	Guangkuo Li, Jianfan Mu, Xuan Liu, Jing He, Fangjie Ji, Weizhan Wang, Yong Liu
Format:	Article
Language:	English
Published:	BMC 2025-10-01
Subjects:	Coronary microvascular function Microcirculatory resistance Coronary heart disease Type 2 diabetes mellitus Angiography-derived assessment of coronary microcirculatory resistance
Online Access:	https://doi.org/10.1186/s13098-025-01916-0