Role of Calcium in Phosphatidylserine Externalisation in Red Blood Cells from Sickle Cell Patients

Phosphatidylserine exposure occurs in red blood cells (RBCs) from sickle cell disease (SCD) patients and is increased by deoxygenation. The mechanisms responsible remain unclear. RBCs from SCD patients also have elevated cation permeability, and, in particular, a deoxygenation-induced cation condu...

Full description

Bibliographic Details
Published in:Anemia
Main Authors: Erwin Weiss, David Charles Rees, John Stanley Gibson
Format: Article
Language:English
Published: Wiley 2011-01-01
Online Access:http://dx.doi.org/10.1155/2011/379894