Regulation of Pdx1 by oxidative stress and Nrf2 in pancreatic beta-cells
The beta-cell identity gene, pancreatic duodenal homeobox 1 (Pdx1), plays critical roles in many aspects of the life of beta-cells including differentiation, maturation, function, survival and proliferation. High levels of reactive oxygen species (ROS) are extremely toxic to cells and especially to...
| Published in: | Frontiers in Endocrinology |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-09-01
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| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2022.1011187/full |