Cell autonomous and non-autonomous consequences of deviations in translation machinery on organism growth and the connecting signalling pathways

Translation machinery is responsible for the production of cellular proteins; thus, cells devote the majority of their resources to ribosome biogenesis and protein synthesis. Single-copy loss of function in the translation machinery components results in rare ribosomopathy disorders, such as Diamond...

Full description

Bibliographic Details
Published in:Open Biology
Main Authors: Agustian Surya, Elif Sarinay-Cenik
Format: Article
Language:English
Published: The Royal Society 2022-04-01
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.210308