Age-dependent structural reorganization of utricular ribbon synapses

In mammals, spatial orientation is synaptically-encoded by sensory hair cells of the vestibular labyrinth. Vestibular hair cells (VHCs) harbor synaptic ribbons at their presynaptic active zones (AZs), which play a critical role in molecular scaffolding and facilitate synaptic release and vesicular r...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Susann Michanski, Timo Henneck, Mohona Mukhopadhyay, Anna M. Steyer, Paola Agüi Gonzalez, Katharina Grewe, Peter Ilgen, Mehmet Gültas, Eugenio F. Fornasiero, Stefan Jakobs, Wiebke Möbius, Christian Vogl, Tina Pangršič, Silvio O. Rizzoli, Carolin Wichmann
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-08-01
Subjects:	aging ribbon synapse synaptogenesis utricle vestibular hair cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2023.1178992/full