Acetaminophen-Induced Liver Injury Alters the Acyl Ethanolamine-Based Anti-Inflammatory Signaling System in Liver

Protective mechanisms against drug-induced liver injury are actively being searched to identify new therapeutic targets. Among them, the anti-inflammatory N-acyl ethanolamide (NAE)-peroxisome proliferators activated receptor alpha (PPARα) system has gained much interest after the identification of i...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Patricia Rivera, Antoni Pastor, Sergio Arrabal, Juan Decara, Antonio Vargas, Laura Sánchez-Marín, Francisco J. Pavón, Antonia Serrano, Dolores Bautista, Anna Boronat, Rafael de la Torre, Elena Baixeras, M. Isabel Lucena, Fernando R. de Fonseca, Juan Suárez
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-10-01
Subjects:	paracetamol PPARα FAAH OEA toxicity hepatic injury
Online Access:	http://journal.frontiersin.org/article/10.3389/fphar.2017.00705/full