IRF4 regulates myeloid-derived suppressor cells expansion and function in Schistosoma japonicum-infected mice

Abstract Background Interferon regulatory factor 4 (IRF4) is a crucial member of the IRF family of transcription factors and is pivotal in orchestrating the body’s defense against tumors and infections by modulating the differentiation and functionality of immune cells. The role of IRF4 in mice duri...

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Bibliographic Details

Published in:	Parasites & Vectors
Main Authors:	Lu Zhou, Peibin Lin, Guorong Deng, Lengshan Mo, Cansheng Hong, Zhihan Jiang, Yiqiang Zhu, Yi Zhao, Yanwei Qi, Tengfei Hu, Qianlian Wu, Jian Zhang, Qingqing Li, Quan Yang
Format:	Article
Language:	English
Published:	BMC 2024-11-01
Subjects:	Schistosoma japonicum Interferon regulatory factor 4 Myeloid-derived suppressor cell Infection
Online Access:	https://doi.org/10.1186/s13071-024-06543-8