Zebrafish model of palmitic acid induced MAFLD recapitulates pathways conserved in mice and humans

Abstract Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) is a major global health issue, affecting millions, yet its underlying molecular mechanisms remain poorly understood. Here, we propose a novel diet-induced zebrafish model to investigate pathophysiology of MAFLD. To validate the m...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Debashruti Bhattacharya, Shruti Kaushal, Barsha Chakraborty, Arnab Raha, Tanoy Dutta, Himanshu Shekhar, Apurba Lal Koner, Saran Kumar, Rajesh Ramachandran, Jaspreet Kaur Dhanjal, Shilpi Minocha
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-09-01
Subjects:	Metabolic dysfunction-associated fatty liver disease Zebrafish Palmitic acid Hepatic injury Transcriptomics
Online Access:	https://doi.org/10.1038/s41598-025-13154-5