Influenza NS1 drives N6-methyladenosine (m6A)-mediated autoregulation of viral mRNA splicing

Influenza A virus replication requires precise balance between unspliced and spliced viral mRNAs. However, the regulatory mechanisms governing viral mRNA splicing remain poorly understood. In this study, we uncover an epigenetic strategy whereby the viral NS1 protein autoregulates its own mRNA splic...

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Bibliographic Details

Published in:	Emerging Microbes and Infections
Main Authors:	Yingyin Liao, Jiayan Liu, Pui Wang, Bobo Wing-Yee Mok, Honglin Chen
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2025-12-01
Subjects:	Influenza virus NS1 M6A modification viral mRNA splicing epitranscriptomics
Online Access:	https://www.tandfonline.com/doi/10.1080/22221751.2025.2572761