GRAM: A GeneRAlized Model to predict the molecular effect of a non-coding variant in a cell-type specific manner.

There has been much effort to prioritize genomic variants with respect to their impact on "function". However, function is often not precisely defined: sometimes it is the disease association of a variant; on other occasions, it reflects a molecular effect on transcription or epigenetics....

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Bibliographic Details

Published in:	PLoS Genetics
Main Authors:	Shaoke Lou, Kellie A Cotter, Tianxiao Li, Jin Liang, Hussein Mohsen, Jason Liu, Jing Zhang, Sandra Cohen, Jinrui Xu, Haiyuan Yu, Mark A Rubin, Mark Gerstein
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2019-08-01
Online Access:	https://doi.org/10.1371/journal.pgen.1007860