Air–Liquid-Interface-Differentiated Human Nose Epithelium: The Benchmark Culture Model for SARS-CoV-2 Infection

COVID-19 has triggered the rapid adoption of human organoid-based tissue culture models to overcome the limitations of the commonly used Vero cell line that did not fully recapitulate SARS-CoV-2 infection of human tissues. As the primary site of SARS-CoV-2 infection, the human nasal epithelium (HNE)...

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Bibliographic Details
Published in:Organoids
Main Authors: Sarah L. Harbach, Bang M. Tran, Abderrahman Hachani, Samantha Leigh Grimley, Damian F. J. Purcell, Georgia Deliyannis, Joseph Torresi, Julie L. McAuley, Elizabeth Vincan
Format: Article
Language:English
Published: MDPI AG 2025-09-01
Subjects:
COVID-19
SARS-CoV-2
human nasal epithelium
Calu-3
variants of concern
VOC
Online Access:https://www.mdpi.com/2674-1172/4/3/21

Internet

https://www.mdpi.com/2674-1172/4/3/21

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