Emerging translational strategies and challenges for enhancing regulatory T cell therapy for graft-versus-host disease

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative therapy for many types of cancer. Genetic disparities between donor and host can result in immune-mediated attack of host tissues, known as graft versus host disease (GVHD), a major cause of morbidity and mortality followin...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Keli L. Hippen, Mehrdad Hefazi, Jemma H. Larson, Bruce R. Blazar
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-07-01
Subjects:	tTreg pTreg iTreg CAR GVHD
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.926550/full