Expression of apolipoprotein C-III in McA-RH7777 cells enhances VLDL assembly and secretion under lipid-rich conditions[S]

Apolipoprotein (apo) C-III plays a regulatory role in VLDL lipolysis and clearance. In this study, we determined a potential intracellular role of apoC-III in hepatic VLDL assembly and secretion. Stable expression of recombinant apoC-III in McA-RH7777 cells resulted in increased secretion efficiency...

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Bibliographic Details

Published in:	Journal of Lipid Research
Main Authors:	Meenakshi Sundaram, Shumei Zhong, Maroun Bou Khalil, Philip H. Links, Yang Zhao, Jahangir Iqbal, M. Mahmood Hussain, Robin J. Parks, Yuwei Wang, Zemin Yao
Format:	Article
Language:	English
Published:	Elsevier 2010-01-01
Subjects:	triacylglycerol hypotriglyceridemia hypertriglyceridemia microsomal triglyceride transfer protein hepatocyte
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520313857