Simvastatin ameliorates oxidative stress levels in HepG2 cells and hyperlipidemic rats

Simvastatin is an established anti-hyperlipidemic drug and few studies have indicated its role in the mitigation of oxidative stress. However, a systematic study considering molecular binding/interaction of simvastatin with anti-oxidant enzymes followed by confirmational in vitro and in vivo studies...

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Bibliographic Details

Published in:	Current Research in Pharmacology and Drug Discovery
Main Authors:	Kanika Verma, Shikha Makwana, Sarvesh Paliwal, Vartika Paliwal, Smita Jain, Swati Paliwal, Swapnil Sharma
Format:	Article
Language:	English
Published:	Elsevier 2022-01-01
Subjects:	Oxidative stress Simvastatin Lipopolysaccharide HepG2 cells Anti-hyperlipidemia
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590257122000086