Negative regulation of APC/C activation by MAPK-mediated attenuation of Cdc20Slp1 under stress

Mitotic anaphase onset is a key cellular process tightly regulated by multiple kinases. The involvement of mitogen-activated protein kinases (MAPKs) in this process has been established in Xenopus egg extracts. However, the detailed regulatory cascade remains elusive, and it is also unknown whether...

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發表在:	eLife
Main Authors:	Li Sun, Xuejin Chen, Chunlin Song, Wenjing Shi, Libo Liu, Shuang Bai, Xi Wang, Jiali Chen, Chengyu Jiang, Shuang-min Wang, Zhou-qing Luo, Ruiwen Wang, Yamei Wang, Quan-wen Jin
格式:	Article
語言:	英语
出版:	eLife Sciences Publications Ltd 2024-10-01
主題:	anaphase-promoting complex/cyclosome APC/C spindle assembly checkpoint SAC MAPK Slp1/Cdc20
在線閱讀:	https://elifesciences.org/articles/97896