SETD2 Regulates the Methylation of Translation Elongation Factor eEF1A1 in Clear Cell Renal Cell Carcinoma

BACKGROUND: SET domain-containing protein 2 ( SETD2 ) is commonly mutated in renal cell carcinoma. SETD2 methylates histone H3 as well as a growing list of non-histone proteins. OBJECTIVE: Initially, we sought to explore SETD2-dependent changes in lysine methylation of proteins in proximal renal tub...

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Bibliographic Details
Published in:Kidney Cancer
Main Authors: Robert Hapke, Lindsay Venton, Kristie Lindsay Rose, Quanhu Sheng, Anupama Reddy, Rebecca Prather, Angela Jones, W. Kimryn Rathmell, Scott M. Haake
Format: Article
Language:English
Published: SAGE Publishing 2022-11-01
Online Access:https://doi.org/10.3233/KCA-220009