Improving case fatality ratio estimates in ongoing pandemics through case-to-death time distribution analysis

Abstract The case fatality ratio (CFR) is a vital metric for assessing the disease severity of novel pathogens. The widely used direct method of CFR estimation—the ratio of total confirmed deaths to total confirmed cases—is inherently simplistic, as it fails to account for the essential time lag bet...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Zia Farooq, Henrik Sjödin, Joacim Rocklöv, Åke Brännström
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-02-01
Subjects:	Case fatality ratio CFR COVID-19 Case-to-death times Distributed-delay method Particle-swarm optimization
Online Access:	https://doi.org/10.1038/s41598-025-89441-y