Harnessing high density lipoproteins to block transforming growth factor beta and to inhibit the growth of liver tumor metastases.

Transforming growth factor β (TGF-β) is a powerful promoter of cancer progression and a key target for antitumor therapy. As cancer cells exhibit active cholesterol metabolism, high density lipoproteins (HDLs) appear as an attractive delivery system for anticancer TGFβ-inhibitory molecules. We const...

詳細記述

書誌詳細
出版年:PLoS ONE
主要な著者: José Medina-Echeverz, Jessica Fioravanti, Nancy Díaz-Valdés, Kathrin Frank, Fernando Aranda, Celia Gomar, Nuria Ardaiz, Javier Dotor, Viktor Umansky, Jesús Prieto, Pedro Berraondo
フォーマット: 論文
言語:英語
出版事項: Public Library of Science (PLoS) 2014-01-01
オンライン・アクセス:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0096799&type=printable