Furin, ADAM, and γ-secretase: Core regulatory targets in the Notch pathway and the therapeutic potential for breast cancer

The activation of the Notch pathway promotes the occurrence and progression of breast cancer. The Notch signal plays different roles in different molecular subtypes of breast cancer. In estrogen receptor-positive (ER+) breast cancer, the Notch pathway regulates the activity of estrogen receptors. In...

全面介紹

書目詳細資料

發表在:	Neoplasia: An International Journal for Oncology Research
Main Authors:	Kuo Yao, Xiang-Yi Zhan, Mei Feng, Ke-Fan Yang, Ming-Sheng Zhou, Hui Jia
格式:	Article
語言:	英语
出版:	Elsevier 2024-11-01
主題:	Breast cancer Notch pathway Furin protease ADAM metalloprotease γ-secretase
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S1476558624000836