Honokiol enhances paclitaxel efficacy in multi-drug resistant human cancer model through the induction of apoptosis.

Resistance to chemotherapy remains a major obstacle in cancer therapy. This study aimed to evaluate the molecular mechanism and efficacy of honokiol in inducing apoptosis and enhancing paclitaxel chemotherapy in pre-clinical multi-drug resistant (MDR) cancer models, including lineage-derived human M...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Xu Wang, Jonathan J Beitler, Hong Wang, Michael J Lee, Wen Huang, Lydia Koenig, Sreenivas Nannapaneni, A R M Ruhul Amin, Michael Bonner, Hyung Ju C Shin, Zhuo Georgia Chen, Jack L Arbiser, Dong M Shin
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Online Access:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0086369&type=printable