Analysis and validation of biomarkers and immune cell infiltration profiles in unstable coronary atherosclerotic plaques using bioinformatics and machine learning

IntroductionDecreased stability of coronary atherosclerotic plaques correlates with a heightened risk of acute coronary syndrome (ACS). Thus, early diagnosis and treatment of unstable plaques are imperative in averting adverse cardiovascular events. This study aims to identify diagnostic biomarkers...

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Bibliographic Details

Published in:	Frontiers in Cardiovascular Medicine
Main Authors:	Pengyue Jin, Shangyu Zhang, Li Yang, Yujie Zeng, Yongguo Li, Renkuan Tang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-02-01
Subjects:	coronary atherosclerosis unstable plaque weighted gene co-expression network analysis machine learning biomarkers immune cell infiltration
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2025.1451255/full