Proteomic analysis defines the interactome of telomerase in the protozoan parasite, Trypanosoma brucei

Telomerase is a ribonucleoprotein enzyme responsible for maintaining the telomeric end of the chromosome. The telomerase enzyme requires two main components to function: the telomerase reverse transcriptase (TERT) and the telomerase RNA (TR), which provides the template for telomeric DNA synthesis....

Full description

Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Justin A. Davis, Andres V. Reyes, Nitika, Arpita Saha, Donald J. Wolfgeher, Shou-Ling Xu, Andrew W. Truman, Bibo Li, Kausik Chakrabarti
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	Trypanosoma brucei cell proliferation telomerase telomere cell growth parasite
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2023.1110423/full