Chimeric Virus-like Particle-Based COVID-19 Vaccine Confers Strong Protection against SARS-CoV-2 Viremia in K18-hACE2 Mice

Virus-like particles (VLPs) are highly immunogenic and versatile subunit vaccines composed of multimeric viral proteins that mimic the whole virus but lack genetic material. Due to the lack of infectivity, VLPs are being developed as safe and effective vaccines against various infectious diseases. I...

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發表在:	Vaccines
Main Authors:	Challika Kaewborisuth, Asawin Wanitchang, Surapong Koonpaew, Kanjana Srisutthisamphan, Janya Saenboonrueng, Rawiwan Im-Erbsin, Manutsanun Inthawong, Piyanate Sunyakumthorn, Theeradej Thaweerattanasinp, Nathiphat Tanwattana, Yuparat Jantraphakorn, Matthew C. Reed, Luis A. Lugo-Roman, Taweewun Hunsawong, Chonticha Klungthong, Anthony R. Jones, Stefan Fernandez, Samaporn Teeravechyan, Eric D. Lombardini, Anan Jongkaewwattana
格式:	Article
語言:	英语
出版:	MDPI AG 2022-05-01
主題:	chimeric virus-like particle vaccine SARS-CoV-2 COVID-19 K18-hACE2 mice
在線閱讀:	https://www.mdpi.com/2076-393X/10/5/786