Radiation-induced brain injury in non-human primates: A dual tracer PET study with [11C]MPC-6827 and [11C]PiB

Radiation-induced brain injury (RIBI) and Alzheimer's disease (AD) share key pathological features, including β-amyloid (Aβ) plaque formation and microtubule (MT) destabilization, both contributing to neurodegeneration. This pilot study assessed Aβ deposition and MT stability in non-human prima...

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Bibliographic Details

Published in:	NeuroImage: Reports
Main Authors:	Naresh Damuka, George W. Schaaf, Mack Miller, Caleb Bradley, Bhuvanachandra Bhoopal, Ivan Krizan, Krishna K. Gollapelli, Christopher T. Whitlow, J. Mark Cline, Kiran K. Solingapuram Sai
Format:	Article
Language:	English
Published:	Elsevier 2025-03-01
Subjects:	Radiation-induced brain injury Aβ deposition Microtubule destabilization Neurodegeneration Radiotracers PET imaging
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666956025000133