Low-intensity pulsed ultrasound inhibits fibroblast-like synoviocyte proliferation and reduces synovial fibrosis by regulating Wnt/β-catenin signaling

Objective: Synovial fibrosis is a characteristic symptom of osteoarthritis (OA), which is closely associated with joint pain and stiffness. Previous studies have reported that low-intensity pulsed ultrasound (LIPUS) can alleviate cartilage degradation in OA. However, the functions and mechanisms of...

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Bibliographic Details

Published in:	Journal of Orthopaedic Translation
Main Authors:	Bo Liao, Mengtong Guan, Qiaoyan Tan, Gailan Wang, Ruobin Zhang, Junlan Huang, Mi Liu, Hong Chen, Kaiting Li, Dingqun Bai, Ying Zhu
Format:	Article
Language:	English
Published:	Elsevier 2021-09-01
Subjects:	Cell proliferation Fibroblast-like synoviocyte Low-intensity pulsed ultrasound Osteoarthritis Synovial fibrosis Wnt/β-catenin signaling
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214031X21000644