ITGA5 induces mesenchymal transformation to promote gliomas progression via PI3K/AKT/mTORC1 signaling pathway

Abstract Glioma is a common malignant tumor of the central nervous system, characterized by high malignancy, strong invasiveness and high recurrence rate. Integrin α5 (ITGA5), a member of the integrin adhesion molecule family, has been reported to be associated with tumor progression and metastasis....

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Moxuan Zhang, Junhong Li, Xianglong Meng, Qiang Sun, Zhengchun Xue, Mingguang Wang, Fei Du, Jian Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Subjects:
Integrin α5
Glioma
Bioinformatics
Proliferation
Prognosis
Online Access:https://doi.org/10.1038/s41598-025-98170-1

Internet

https://doi.org/10.1038/s41598-025-98170-1

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