A Bitter Taste Receptor as a Novel Molecular Target on Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma

Cancer-associated fibroblasts (CAFs) execute diverse and complex functions in cancer progression. While reprogramming the crosstalk between CAFs and cancer epithelial cells is a promising avenue to evade the adverse effects of stromal depletion, drugs are limited by their suboptimal pharmacokinetics...

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書誌詳細

出版年:	Pharmaceuticals
主要な著者:	Jessica Hung, Samantha M. Perez, Siva Sai Krishna Dasa, Sarah P. Hall, Danielle B. Heckert, Brian P. Murphy, Howard C. Crawford, Kimberly A. Kelly, Lindsey T. Brinton
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2023-03-01
主題:	TAS2R9 CXCR2 inhibitor targeted liposome stromal therapy
オンライン･アクセス:	https://www.mdpi.com/1424-8247/16/3/389